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A drug-induced depression may not run on a mainly serotonergic mechanism, so an agent with a wider receptor footprint (SERT inhibition plus 5-HT1A agonism, 5-HT3 and 5-HT7 antagonism, and 5-HT1B partial agonism) looked better matched to the uncertainty about what was actually driving the episode

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We recommend limiting alcohol, especially during the early adjustment period

Food and Drug Administration (FDA) has approved Ozempic to reduce the risk of kidney disease worsening, kidney failure (end-stage kidney disease), and death due to cardiovascular disease in adults with type 2 diabetes and chronic kidney disease (CKD)