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Despite their desire to leave and the negative consequences of tobacco use, individuals struggle to maintain tobacco abstinence and find themselves relapsing into tobacco use

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In a cross-sectional study that focused on HPHCs in salivary and urine samples, detected salivary levels of N 1 -nitrosonornicotine (NNN) in e-cigarette users overlapped with those measured in cigarette smokers, but urine levels of NNN were very low or not detectable in e-cigarette users [41]

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