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101 Data on the NAC effects in COPD suggest that NAC reduces elastase activity, 99 hinders the loss of pulmonary glutathione, abolishes the effects of cigarette smoke, prevents thickening of the airway wall, and reduces the risk of exacerbations

A recent study combining single-nucleus sequencing and spatial transcriptomics pinpointed the human hypothalamic GLP-1R-LepR co-expressing cluster, which strongly correlated with the mouse hypothalamic cluster that exhibits the second highest expression of GLP-1R in the hypothalamus [76]

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