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Withdrawal symptoms can last from a few days to a couple of weeks and include: Cravings Insomnia or restless sleep Headaches Irritability, depression, and anxiety Increased appetite or weight gain Difficulty concentrating Body aches and pains Gastrointestinal issues Nicotine Addiction The US Food and Drug Administration (FDA) officially recognized Nicotine as an addictive drug in 1994 and took control over federal Nicotine regulations in June of 2009