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For a deeper overview of incretin therapies and how they compare across medication classes: GLP-1 and GIP/GLP-1 Receptor Agonist Interactive Comparison Chart Common GLP-1 Medications Several GLP-1 receptor agonists are widely used in clinical practice

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Data availability The source data supporting the findings of this article are included in this article and its supplementary information files

Furthermore, the agonists of Nrf2, which serve as pivotal upstream regulators of SLC7A11, function as indirect activators of System Xc-, as they regulate SLC7A11 at the transcriptional level rather than directly modifying the functional activity of the complex (139)