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This can lead to a buildup of acetaldehyde, a toxic byproduct of alcohol metabolism that can cause headaches, nausea, and other unpleasant symptoms

Furthermore, APAP exposure significantly depletes glutathione [68], suggesting that repeated exposure to the drug is potentially more hazardous than a single exposure.Although APAP metabolism is well characterized, a high degree of variability in APAP metabolism within the pediatric population has been observed, and the factors affecting this variability are poorly understood [69]

sizes for flexible daily use

This moves the formulation decision from guesswork to objective data