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Lack of long-term toxicity data and systematic risk assessment strategy are the primary hindrances for the regulators to outline evidence-based policy recommendations 3
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Internal collagen defects Heart murmur (mitral valve prolapse) and weakened walls of intestines, arteries, and uterus, which may rupture Autonomic dysfunction transient loss of consciousness, palpitation, dizziness, chest pain, and shortness of breath Postural orthostatic tachycardia syndrome (POTS) fast heartbeats, which particularly occur on postural change or standing Recurrent pneumothorax these can be the initial presentation of EDS What are the complications of EhlersDanlos syndrome