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Matarazzo was actually born with this and the Duffer Brothers would later write it into the show as away to explain why his character was missing a few teeth in Season 1
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Various targeted sequencing panels have recently been developed to efficiently determine tumour mutation burden, and a strong correlation has been observed between targeted sequencing and whole genome sequencing in some studies.31 32 Another limitation of our study was recall bias, which cannot be ruled out when obtaining smoking information, even in a prospective cohort study
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