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By contrast, the stress sensor GADD45 was detected within only early differentiating IRS cells (supplementary figure 3c), while the ROS-protective protein heme oxygenase-1 (HO-1) was intensely expressed in a small subset of IRS cells located usually in the upper follicle, at the level of the sebaceous gland, where IRS cornification is advanced to complete (supplementary figures 3g and 3h)

Prescription medications are often used to treat PCOS, they can be effectivem but some women experience side effects

B12 binds to haptocorrin, which helps it reach the small intestine for absorption

The endometrial cells can even invade through the wall of the intestines