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21 One strategy for attracting new customers was to conduct experimental studies to test new flavoursa vital sales factor, 21,22 and research conducted for USST found that communications stressing taste, flavour and freshness were most successful in inviting trial of ST

However, when discussing amount and frequency of use, those who used e-cigarettes, pipes, or waterpipes reported they had greater difficulty quantifying the amount or times they used their products in a day than those who smoked cigarettes or used smokeless tobacco

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The enhanced expression and release of SASP factors, including cytokines, chemokines, cell adhesion molecules, and matrix metalloproteinase (MMPs), promote and facilitate the recruitment, infiltration, and accumulation of immune cells in tissue [15, 17]