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However, there still may be some bias (toward a positive association) from including all smoking status groups in the same model, especially if there is an unaccounted-for interactive effect between EC use and smoking history (such that those with longer smoking histories have higher health risks) which could falsely appear to carry over to PWNS

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Puff length also influences how much nicotine you inhale

If you wait too long in between cigarettes, your body will produce withdrawal symptoms, and these sensations prompt you to smoke another cigarette