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More recently, gene therapies have been FDA-approved for the treatment of hemophilia

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(iv) Determining national per capita expenditures for Parts A and B services under the original Medicare fee-for-service program for assignable beneficiaries for purposes of capping the regional adjustment to the ACO's historical benchmark according to 425.601(a)(8)(ii)(C) and 425.656(c)(3), capping the prior savings adjustment according to 425.658(c)(1)(ii), capping the prepaid shared savings multiplier according to 425.640(f)(2)(v), and calculating the HEBA scaler according to 425.662(b)(2)