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however, this relationship seems more complex and could be mediated by genetics Diet, lifestyle and behaviour, as well as perturbations of the gut microbiota through use of antibiotics, might also have important roles in disease pathogenesis Modification of IBD risk factors offer avenues of intervention for disease prevention and improvement of natural history Abstract IBD, comprising Crohn's disease and ulcerative colitis, is a chronic immunologically mediated disease at the intersection of complex interactions between genetics, environment and gut microbiota
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