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This initial drop in copy number could result from CSE-induced oxidative stress damaging mitochondria and stimulating their clearance via mitophagy and leading to reduced mtDNA content

He ran back-cover parodies of cigarette ads and cigarette companies in HUSTLER that made MAD Magazine cigarette ad parodies seem tame

This may involve avoiding situations or places associated with smoking, finding alternative activities to replace smoking, or practicing relaxation techniques to cope with stress or anxiety