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Vaping of 1 disposable Puffbar E-cigarette containing synthetic cooling agents would expose a user to amounts of WS-3 (1,880-10770 g/g) that exceed the threshold of concern by ~29-176 fold, or ~26-598 fold for WS-23 (3,940-36660 g/g)

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Blood samples for pharmacokinetic assessment of sildenafil were collected at 3, 4, 6, 8, 12, and 24 h after administration of vericiguat/placebo on days 13, 14, and 15

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