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In this study, we used a G protein-coupled receptor-activated DA fluorescent probe (GRABDA1m) and optical fiber photometric recording equipment to monitor the dynamic changes and kinetics of DA release in the NAc of mice exposed to different e-cigarette aerosols, including nicotine, nicotine benzoate, nicotine tartrate, nicotine lactate, nicotine levulinic acid, nicotine malate, and nicotine citrate

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Their study demonstrated that changes in mitochondrial DNA can have a significant impact on sperm quality and its swimming ability 56

As e-cigarettes are a relatively recent phenomenon, there are no long-term studies that can establish their safety