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Thus, to deal with their growing use, different reimbursement policies are also being introduced by the government

The two major incretins are GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)

The selectivity data showing absence of ACTH/cortisol stimulation come from swine studies, and while swine GH physiology closely resembles that of humans, direct translation cannot be assumed without clinical validation

GLP-1 receptor agonists were not developed to treat autoimmune diseases, though emerging research has identified potential anti-inflammatory mechanisms in some autoimmune conditions