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11.5 Pharmacokinetics and bioavailability It is evident that following oral administration, resveratrol is rapidly absorbed in the gastrointestinal tract (75%) with an extensive first-pass metabolism in the intestine and liver, lowering its oral bioavailability (ranging from 2.6 to 75% in humans and 2029% in rats fed 50 mg/kg) [198]

Learn More from the Experts For deeper insights into Setria's ongoing research and applications, check out our recent podcast interview with Katie Emerson and Tony Miano from Kyowa Hakko, recorded at Expo West 2025

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Glutathione is a powerful antioxidant which naturally occurs in the skin where it serves to help defend it against the visible effects of environmental damage