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It may also be involved in the human sense of the progress of time, since it can create an anticipatory signal of how people may feel as opposed to how they feel now

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If you have any of the following, call your doctor and/or go immediately to the closest hospital emergency department: Severe chest pain or pressure, especially if it radiates to the arm, neck, or back Shortness of breath Severe sweating Vomiting followed by severe chest pain Vomiting blood Dark, tarry stools Difficulty swallowing solids or liquids What is the esophagus