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Reduced appetite and food intake via central nervous system GLP-1 receptor activation [1]

Interestingly, no body weight gain, a typical side effect of PPAR full agonists, was observed in comparison to vehicle control (Lamotte et al., 2014)

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Conversely, cardiac catheterization patient volume showed minimal growth in 2019 (0.5%), followed by a substantial decline in 2020 (-16.6%), with continued downward utilization trends in subsequent years, ultimately reaching -14.4% by 2023