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Then in the 1990s, with the Master Settlement looming and the lobby for FDA regulation underway, attention shifted to an emerging business strategy known as "relationship marketing." Where traditional marketing emphasized individual sales, this new model traded in human economics:investments in individual customers, through direct communication and rewards, could pay off in long-term loyalty and word-of-mouth promotion

At any rate, considering that the main objective of any treatment for patients with CS is to reestablish normal function of the nasosinusal mucosa and the evidence that cigarette smoking impairs mucociliary transport, reducing cilia beat, the ciliogenesis or epithelial regeneration process, a proper education for these patients towards interrupting cigarette smoking as well as reinforcing campaigns against smoking are extremely important to control this disease that has a major socio-economic impact