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Tobacco Harm Reduction: A Burning Issue for Asia Harry Shapiro The focus of this GSTHR briefing is Asia

This reduces the risk of leaks or spills and ensures consistent performance

Grading of recommendations Recommendations are graded according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system.21 Whether a recommendation is strong or conditional will depend on considerations such as certainty in estimated effects of an intervention, including magnitude, as well as estimates of how patients value and prioritize outcomes, variability of these estimates, and wise use of resources