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Recap Lung cancer, like other cancers, remains a significant global health challenge, but advancements in diagnosis, treatment, and prevention are improving outcomes for patients

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Despite the lack of carcinogenicity evidence, it has been reported that nicotine promotes tumour cell survival by decreasing apoptosis and increasing proliferation [49], indicating that it may work as a tumour enhancer

Efficacy of e-cigarettes in reducing smoking and in harm reduction, their safety over the long term, and the effect of their sale on that of combustible cigarettes are all issues that need to be further investigated.