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The end result is gastric atrophy and depletion of intrinsic factor leading to poor absorption of food-bound, free, and biliary vitamin B 12 .2 Malabsorption is more complete and severe in PA compared to food-cobalamin malabsorption which is more partial in nature,2 and so the manifestations are more overt and severe in PA

Originally developed to treat type 2 diabetes, it works by activating GLP-1 and GIP receptors, which regulate blood sugar and appetite control

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