Protein kinase C in rat brain cortex and hippocampus: effect of repeated administration of fluoxetine and desipramine
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Boost your levels by eating: Sulfur-Rich Foods: garlic, onions, broccoli, cauliflower Vitamin C Foods: oranges, kiwi, papaya, strawberries Selenium Sources: eggs, fish, whole grains Protein & Amino Acids: chicken, lentils, beans Healthy Habits: good sleep, regular exercise, go easy on alcohol, manage your stress Sometimes, these lifestyle changes do more for your glutathione levels than popping a pill
This system is highly expressed in astrocytes, the main GSH synthesizing cells in the brain, and is regulated by various factors, including oxidative stress and inflammatory cytokines Once synthesized, GSH can be metabolized by various enzymes, including glutathione S-transferases (GSTs), which conjugate GSH with xenobiotics and endogenous electrophiles for elimination, and gamma-glutamyl transpeptidase (GGT), which cleaves GSH into its constituent amino acids and generates extracellular glutamate, a major neurotransmitter in the brain