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Secondhand smoke refers to the fumes that are emitted when smokers use: cigarettes pipes cigars other tobacco products Firsthand smoking and secondhand smoke both cause serious health effects

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Although the effects of smoking are not the same as those of nicotine, there is clinical evidence that suggests that nicotine and/or its metabolites, such as cotinine, are responsible for the beneficial effect of smoking in patients with active UC

Less common causes include fungi or parasites