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With semaglutide-delayed gastric emptying, this window may need to be even longer, up to 5 hours for some people

Less common side effects can be constipation, abdominal pain, headaches, fatigue, dizziness, and adverse reactions including nausea

While the medication does not directly cause muscle weakness through a neuromuscular mechanism, the combination of fatigue, gastrointestinal symptoms, rapid weight loss, and dietary changes associated with semaglutide therapy creates a clinical context where weakness can reasonably occur as a secondary phenomenon

The first week is crucial as Ozempic begins working to help regulate blood sugar and support weight loss