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But Roehrs made strong cases about the inconsistency and poor design of the older studies that comprise the only published evidence for a marijuana-REM sleep link, and that his and Lundahls work had a more careful methodology behind it: Their study didnt just compare smokers to nonsmokers, which can introduce various confounds, but also, through the use of the placebo weed, it was able to more intricately track the short-term sleep effects of smoking marijuana on heavy users