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In addition, the treatment with NP4 reduced the level of anti-inflammatory M2-type macrophages by 20% in comparison to the treatment with NP2 (Supplementary Fig

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Many identified metabolites, such as those containing sulfur and phenol, are known to be toxic to enterocytes, disrupt intercellular tight junctions (TJ), and stimulate bacterial translocation, all of which support this idea (van der Poll et al., 2017)

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