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Niacin deficiency delays DNA excision repair and increases spontaneous and nitrosourea-induced chromosomal instability in rat bone marrow

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Other research shows that In addition to having slower delivery, NRT only offers 30% to 75% of the amount of nicotine that would be acquired from smoking. However, the same authors state that use of emerging nicotine delivery systems, such as e-cigarettes, should continue to be discouraged. This is curious, when Cochrane, in 2023, found high certainty evidence that nicotine e-cigarettes are more effective than traditional [NRT] in helping people quit smoking. Further research has found vapes to be almost twice as effective as NRT

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