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Switching plan: what timing is safest if changing therapies

Its recommended that any changes in the therapeutic effects of oral medications be monitored and that dosing be adjusted as necessary

Keep in mind that there are versions of semaglutide and tirzepatide that are approved for either weight loss (Wegovy, Zepbound) or diabetes (Ozempic, Mounjaro), but not one version that's approved for both, even though effects should be the same between them

For in-use pens that have already been stored at room temperature as per guidance, an additional overnight exposure is less concerning, provided the cumulative room-temperature storage does not exceed 6 weeks