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Kevin Sheng-Kai Ma, DDS, FRSPH, FRSM, international scholar at the Center for Global Health at the Perelman School of Medicine at the University of Pennsylvania and lead author of this study, told Medical News Today that he and his colleagues were not surprised by these findings, as these [obesity and obesity-related issues] are indications for GLP-1RA that have been approved in recent years. That said, clinicians are encouraged to monitor and continue assessing patients receiving GLP-1RA [drugs], he advised

Lastly, we only investigated carnitines in this study, because the targeted approach could only measure a limited set of metabolites and funding was limited (34)

We haven't done any trials

Frequency depends on your goals and medical needs