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Interestingly, they found that platelets from exposure to ECV extracts caused remarkable up-regulation in proinflammatory markers of gC1qR and cC1qR and led to a significant increase in the deposition of C3b compared with tobacco smoke extracts

132 The ranks of different interventions could also be adjusted according to other criteria besides cost-effectiveness, such as equity impact or financial risk protection afforded

Patches can also cause dry mouth, abnormal dreams or sleep disturbance (removal of the patch before bed may help if this is severe)