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A Three-Cornered Competition Conceptually, the market can be simplified into a three-cornered contest for nicotine consumers: Lawfully supplied but highly dangerous combustible products that are widely available, such as cigarettes, which cause the main burden of tobacco-related disease Popular but illicit, unregulated smoke-free products with uncertain risks and negative crime-related consequences, such as illegally supplied Chinese disposable vapes Lawfully supplied and regulated smoke-free products that are provably far safer than smoking but meet only a small fraction of consumer demand The FDAs main efforts in shaping this marketplace have been aimed at preventing youth uptake by creating high barriers to entry for lawful vapes