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Their data showed that, while the octanol-water partition coefficient (LogP) increased linearly with molar volume, the membrane-water partition coefficients (LogB), increased initially with LogP for the smaller molecules, but then followed a more parabolic relationship with respect to larger V m

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Because the circuits are partly distinct, the effects tend to add rather than overlap, and the combination can deliver more total appetite suppression at amounts that neither compound would need to reach alone

Appl Biochem Biotechnol 165:978988 Icel E, Suleyman H, Yazici GN, Bakan N, Sunar M (2020) Effects of adenosine triphosphate on methanol-induced experimental optic nerve damage in rats: biochemical and histopathological evaluation