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However, when ROS and RNS are present in excessive amounts and/or in the form of highly reactive free radicals such as superoxide anion and hydroxyl radical, they oxidize susceptible biomolecules such as membrane lipids, cellular proteins, and nucleic acids, leading to disruption of normal cellular functions (35)

In short, this study was conducted to investigate the protective effect of maternal HMSeBA supplementation in regulating ER stress signal induced by LPS in the jejunum of offspring, and the direct regulation of HMSeBA on ER stress signal induced by ROS and the expression of selenoproteins in IPEC-J2 cells