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As the fragrance evolves, a majestic tobacco heart takes over

This month (November 23, 2018) marks the 20th anniversary of the landmark 1998 legal settlement between the states and the tobacco companies (the Master Settlement Agreement or MSA), which required the companies to pay more than $200 billion over time as compensation for tobacco-related health care costs, restricted some forms of tobacco marketing and provided funding for a national public education campaign to prevent youth tobacco use

Within the broad scope of research topics in the literature, the papers selected for this review focused on e-cigarettes in the context of key topics related to tobacco harm reduction, including aerosol chemistry studies, toxicological assessments of e-cigarette aerosols with in vitro and in vivo in comparison to cigarette smoke, and clinical investigations that examined the short- and long-term benefits of switching to e-cigarettes for adult smokers (Table 1)

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