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Disruption of normal cannabinoid receptor activity causes the mental and physical effects of a pot high. In addition, smoking pot increases levels of dopamine and serotonin, two neurotransmitters implicated in sleep, mood and pleasure

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Coffee and Cigarettes, written and directed by Jim Jarmusch (Down by Law) co-stars Steven Wright (Natural Born Killers), Isaach De Bankol (Casino Royale), Jack White (Cold Mountain), Taylor Mead (Midnight Cowboy) and features atmospheric black & white photography courtesy of Robby Mller(Down by Law), Tom DiCillo (Stranger Than Paradise), Frederick Elmes (Blue Velvet) and Ellen Kuras (Eternal Sunshine of the Spotless Mind)."

Retrieved December 30, 2008