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CS exposure in humans involves complex variables such as inhalation dynamics, metabolic processing and tissue clearance that are difficult to replicate in cell culture systems

We were able to obtain five brands of commercial charcoal-filter (CF)-containing cigarettes (Lark, Parliament, Kent, Seven Stars, and Mevius) and compared the levels of radicals to those of cellulose acetate filter (AF) research cigarettes (3R4F and 1R6F) and four popular commercial AF cigarettes (Marlboro Silver, Camel Blue, Pall Mall Orange, and Newport Red) under ISO and CI methods

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