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Cigarette smoking: Natural history of a dependence disorder

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E-cigarettes are likely less harmful to the respiratory system than combustible cigarettes,[9] but new data suggest that e-cigarettes are associated with independent respiratory health risks, most notably acute EVALI.[10] Weaker associations have been shown between e-cigarettes and chronic respiratory diseases, including higher incidence of chronic obstructive pulmonary disease,[38] asthma,[39-43] and obstructive lung disease not otherwise specified.[44-46] Because the data on the respiratory effects of e-cigarettes are expansive, we provide an overview of the key points