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| Protocol | Primary Receptor Targets | Typical Dose Range | Peak Plasma Time | Common Adverse Events (Incidence) | Recommended Spacing | Bottom Line Assessment | ||||||| | Melanotan-2 Monotherapy | MC1R, MC3R, MC4R, MC5R (non-selective) | 5001000 mcg subcutaneous | 12 hours | Nausea (4060%), flushing (3050%), hyperpigmentation (90%+), spontaneous erections (males, 2040%) | Daily or alternate days