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Cardiac myocytes derived from hESCs with BMAL1 deficiency exhibit typical phenotypes of dilated cardiomyopathy, including reduced contractility, maladjustment of calcium, and myofilament disorders, as well as compromised mitophagy and mitochondrial dysfunction through reduced BNIP3 protein levels [36]

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The MPs abundance in farmed soil in Wuxi and Nanjing ranged from 420 to 1290 items/kg 26 , while in Hangzhou Bay, southeast China, the abundance was 263 items/kg in unmulched land and 571 items/kg in mulched land 104

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