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For example, a study on macrophage FAS found that IL-4 can activate sterol regulatory element-binding protein 1 (SREBP1), triggering the de novo lipogenesis (DNL) program, separating it from the cells antioxidant defense by depleting NADPH, thus increasing ROS levels

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all adult smokers The CDC data showed wide state-by-state variation in reported rates of smoking during pregnancy

Code availability Not applicable Funding The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University, Saudi Arabia, for funding this work through the Large Research Groups Program under grant number R.G.P2/274/44