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As is the case with these drugs, nicotine produces a tolerance effect on the body, requiring the user to consume more of the chemical to experience the same high. Tobacco User Statistics and Trends Per a study published in the journal Addict Health , nicotine constitutes approximately: 3.8 percent of tobacco weight in pipe tobacco 1.8 percent of tobacco weight in domestic cigarettes 1.2 percent of tobacco weight in imported cigarettes Scientists estimate that the nicotine content in one can of snuff or dip is the equivalent of about 80 cigarettes or four packs

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