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10.1016/j.jep.2023.117686 201 Twarda-ClapaA.OlczakA.BiakowskaA

GHK-Cu Research# GHK-Cu research spans both laboratory and limited human studies: Wound healing : Accelerated wound closure in animal models and small human studies Skin rejuvenation : Human studies demonstrating improved skin thickness, elasticity, and collagen density with topical application Hair growth : Studies showing increased hair follicle size and proliferation Gene modulation : Comprehensive genomic studies mapping its effects on ~4,000 genes Anti-fibrotic effects : Research suggesting reduction of scar tissue formation GHK-Cu benefits from some human data in dermatological applications and a longer history of commercial use, though large-scale clinical trials remain limited

Clinical practice guidelines change over time as our knowledge of disease states evolves