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In both young and aged mice, acute exposure to injected cigarette smoke condensate caused the formation of dysfunctional RPE clusters with decreased expression of core RPE cell function genes, decreased chromatin accessibility, and decreased expression of "hallmarks of aging" genesgenes that prevent or regulate processes linked to aging
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[38] E-cigarette fluid is made of various hazardous substances, including nicotine, polycyclic aromatic hydrocarbons (PAHs), and metallic elements
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