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Possible long-term effects of nicotine Constant urge to have more nicotine Early aging and skin wrinkles Ongoing stomach issues like ulcers Heart attacks and other heart issues Problems with eyesight Changes to how things taste and smell Loss of muscle Problems with focus, memory, and learning Long-term mental health issues like depression and anxiety

Studies highlight fewer combustion toxins but still identify IQOS respiratory risks , including airway irritation and potential IQOS lung damage with long-term use

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