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Description

The team at BodEvolve has covered this honestly in their guide on bariatric surgery for severe obesity, where Dr

p-AMPK inhibits the expression of SREBP-1c via Ser372 phosphorylation and blocks SREBP-1c nuclear translocation, thus inhibiting the transcription and translation of SREBP-1c target genes such ACC1, FAS, and stearoyl CoA desaturase 1 (SCD1) (Li et al., 2011b)