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MiR-142 and miRNA-650 might be involved in regulating ALOX15[95]

Curiously, dopamine-producing neurons outside of the SN tend not to be affected, though many other neuronal types glutamatergic, cholinergic, tryptaminergic, GABAergic, noradrenergic, adrenergic show grievous cytoskeletal damage, according to Braak and Braak

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In animal studies, increased glutathione was associated with lower uric acid levels, indicating that enhancing antioxidant capacity may help manage uric acid