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It is split into two parts, A Global Perspective and Regional and National Insights | GSTHR Current and past trends in tobacco and e-cigarette use and the impact of control measures: an analysis of survey data and other evidence (2021) Current and past trends in tobacco and e-cigarette use and the impact of legislative and regulatory controls on smoking and e-cigarette use behaviours are outlined in this multi-method research | NatCen, UK Updated May 2026

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Food and Drug Administration (FDA) as Generally Recognized As Safe (GRAS) for use as a direct food additive, including frozen foods such as ice cream and frozen desserts.The GRAS designation is specific to its use in food, and does not apply to other uses